The molecule your cells run on.

NMN+ · NAD⁺ Precursor
  • Third-party tested
  • Research-backed dose
  • Vegan & Non-GMO
In the science & press

The most talked-about molecule.

See who's writing about NMN →

Longevity · The Problem

Aging starts in your cells.

Inside every cell is a molecule called NAD⁺ — the spark your body uses to turn food into energy, repair DNA, and keep cells working the way they did in your twenties. And NAD⁺ doesn't hold. In the human tissues researchers have measured — skin, brain, muscle — levels run lower with age, and activity levels appear to matter as much as the years do.*

Energy runs low

Less NAD⁺ means the mitochondria — your cells' power plants — make less usable energy. It surfaces as afternoon crashes and slower recovery.

Repair slows down

NAD⁺ fuels the enzymes that patch damaged DNA and clear worn-out cells. As it declines, that daily maintenance falls behind.

Cells age faster

With less NAD⁺, the systems that keep cells youthful and resilient lose momentum — and the effect compounds with every passing year.

10–25%reported fall in tissue NAD⁺ across adult life*
See your NAD⁺ decline →

*Range reported across human tissue studies (skin, brain, muscle); whole-blood NAD⁺ shows no consistent age decline. Individual levels vary and are not measured by this website. See our sources → This statement has not been evaluated by the FDA. NMN+ is not intended to diagnose, treat, cure, or prevent any disease.

A man taking a Sigma Formulas NMN+ capsule at a sunlit kitchen counter
Science · How NMN Works

See what time takes from your cells.

NAD⁺ powers energy, repairs DNA, and keeps cells resilient — and it falls as you age. Drag to your age. Then switch on NMN+ and watch what a precursor gives back.

Drag the slider · toggle NMN+
σ // NAD⁺ Lifespan Instrument Modeling
Age
45
NAD⁺ (modelled)
91%
With a precursor
94%
Difference
+3 pts
100 85 70 20 40 60 80 AGE
20 80
NMN+ support See NAD⁺ with a precursor
Simplified illustration, not a measurement of you. Human studies that measure NAD⁺ in tissue (skin, brain, muscle) generally report levels roughly 10–25% lower across adult life — not the dramatic collapse often shown online. Whole-blood NAD⁺ shows no consistent decline with age. Individual levels vary widely. See the studies and what each one actually found →*
The Bigger Picture
You are 30 trillion cells. Every one runs on the same molecule.

That molecule is NAD⁺. Keep it topped up, and you support the machinery behind energy, repair, and resilience — in every cell, at once. NMN+ exists for exactly one job: to give it back.

An opened Sigma Formulas shipping box with the NMN+ jar and insert card
How It Works

From capsule to cell, in three conversions.

01 / INGEST

NMN enters circulation

Nicotinamide Mononucleotide is absorbed and transported into cells, where it serves as a direct building block for NAD⁺.

02 / CONVERT

NAD⁺ is synthesized

Cells convert NMN into NAD⁺, replenishing the coenzyme required for mitochondrial energy production and DNA repair.

03 / ACTIVATE

Sirtuins engage

Restored NAD⁺ availability supports sirtuin activity — proteins tied to cellular resilience and healthy-aging pathways.

Formula · Fully Disclosed

Every capsule, on the record.

No proprietary blends. No hidden fillers. Every ingredient is dosed to published research levels and disclosed in full — read it like a lab printout, not ad copy.

The seven NMN+ actives shown as powders with names, doses and roles

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Hypromellose (vegetable capsule). Nothing you can’t see on the label.

Proof · Clinically & Third-party Tested

A claim is only as good as its proof.

Anyone can print "99% pure" on a label. We publish the receipt. Every production batch of NMN+ is sent to Eurofins — one of the world's largest independent testing networks — and screened for purity, potency, and contaminants before a single bottle ships.

And the NMN itself is UTHEVER®, an NMN backed by a published, randomized, placebo-controlled human clinical trial — so the core active isn't just tested, it's studied.

σ // Batch VerificationVerified

Every batch tested by Eurofins for purity, potency & contaminants. Certificates of Analysis are published on our Lab Reports page once testing is complete.

Purity Potency Contaminants
σ // Clinically StudiedUTHEVER®

Our NMN is UTHEVER® — the subject of a published randomized, double-blind, placebo-controlled human trial. Clinical evidence stands behind the ingredient, not marketing copy.

Human trial Randomized Placebo-controlled
The Difference

Not all NMN is created equal.

Most NMN products ask for trust. Ours shows its work — here's NMN+ against common practice across the category.

What mattersSigma FormulasNMN+Typical NMN products
Clinical evidenceTested in humans — randomized, placebo-controlled trialRarely studied in people
NMN sourceUTHEVER® — clinically studiedUnbranded, origin unclear
LabelEvery dose disclosedProprietary blends common
TestingEurofins — every batchRarely published
NMN per serving500 mg — research-levelVaries widely
Absorption supportBioPerine® includedUsually absent
CapsuleVegan HPMC, non-GMOOften gelatin

Category-level comparison reflecting common practices among NMN supplements — not a claim about any specific brand.

Get Started

Choose how you take it.

Subscriptions run for a 2-month minimum, then pause or cancel anytime from your account.

One-Time

60 caps · 1-month supply
$34.99one time
  • Full-dose, disclosed formula
  • Third-party lab tested
  • Free US shipping over $60
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Questions

Before you start.

What is NMN, and why not just take NAD⁺? +
NAD⁺ is poorly absorbed when taken orally. NMN (Nicotinamide Mononucleotide) is a direct precursor your body readily converts into NAD⁺ — which is why it's the preferred delivery route.
How long until I notice a difference? +
Most people take NMN+ daily for 4–8 weeks before evaluating effects, since replenishing cellular NAD⁺ is a gradual process. Consistency matters more than any single dose.
Is it third-party tested? +
Yes. Every batch is tested by an independent lab for purity and potency before release. Certificates of Analysis are available on request.
Can I cancel my subscription? +
Subscriptions run for a 2-month minimum (two deliveries). After that you can pause or cancel anytime — no fees — directly from your account dashboard.
Is NMN safe? +
NMN has been generally well tolerated in published human studies at doses comparable to ours. Supplements aren't right for everyone, though — talk to your healthcare provider before starting, especially if you're pregnant, nursing, taking medication, or managing a condition.
Why UTHEVER® NMN specifically? +
UTHEVER® is one of the few NMN ingredients evaluated in a published randomized, double-blind, placebo-controlled human trial. We'd rather build on an ingredient with public evidence than an unbranded powder.

Give your cells back what time takes away.

NMN+ · 60 capsules · a 1-month supply.

The Longevity Briefing

Short, sourced notes on NAD⁺ research and new formulas. No hype. Unsubscribe anytime.